The high-volume usage of supplementary cementitious materials (SCMs) has gained importance in the construction sector and is extending to all types of applications of concrete. The initial interest of the industry in such materials was mainly to decrease the cost of cement or concrete, and to increase the strength. However, the emphasis is now shifting to employing SCMs to increase durability and enhance the sustainability of concrete technology. The presentation will cover the advantages of concretes with SCMs over those with only ordinary portland cement, parameters that can be used to compare durability and sustainability potential and some limitations that have to be addressed when SCMs are incorporated in concrete. The SCMs considered will include fly ash, ground granulated blastfurnace slag and a combination of limestone calcined clay.